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These melanin-independent mechanisms provide cellular UV protection additive to the physical UV-screening function of melanin , explaining why MT-1 provides photoprotection in EPP patients where the primary clinical endpoint is protection from visible light rather than UV-induced tanning

Additionally, the oral formulations must be taken at strict dosing schedules which is the same time every day and on an empty stomach

The findings were presented at ENDO 2026 recently, the annual meeting of the Endocrine Society, and are being seen as an important step towards understanding how modern anti-obesity medicines work beyond simply reducing food intake