Clinical criteria require a documented diagnosis of obesity (BMI 95th percentile for age and sex, or BMI 30 kg/m at age 17+) plus at least one weight-related comorbidity, such as type 2 diabetes, prediabetes, hypertension, or dyslipidemia
, but can it work in humans, safely and reliably

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And then I thought to myself, "Gosh, this is like torture sometimes having to really go, I can only eat this much or managing my caloric intake." And then we got it within the practice here and I thought, "I'm just going to go back on this at a really low dose to help me more sanely manage this weight that I had worked so hard to achieve." And not just from, of course, the surgical work that I had put into it, but also the work afterwards