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Daily challenge with CARN for 5 days before and after a single dose of MTX induced 51% and 27% increase in serum albumin level compared with the MTX and MTX-MD groups, respectively

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In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [ 3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days

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