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The GLP-1 receptor gene (GLP1R) and other peptide-pathway variants influence how your body processes the medication and tolerates dose escalation

GLP-1 also protects HT22 cells against oxidative stress-induced cell death (183)

Seek urgent medical advice if you develop severe vomiting, dehydration, persistent abdominal pain, or signs of allergic reaction whilst taking both medications

Published evidence comparing drug costs to outcome measures for health insurers/systems remains sparse, but one study compared the treatment of type 2 diabetes with insulin versus treatment with GLP-1s and found that the higher drug and outpatient costs associated with GLP-1 treatment were offset by a reduction in healthcare costs from emergency visits and inpatient admissions