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The elevation of ketone bodies, particularly BHB, underscores a pivotal aspect in understanding both the risks of SGLT2 inhibitor-associated DKA and their potential cardioprotective benefits, highlighting the necessity for further research in this area to unravel the complex mechanisms involved

Using aortic rings, it was reported that the ASX vasorelaxation effect was NO-dependent, at the low concentration, and NO-independent, at the high dose [34]

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