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Analysis of genetic polymorphism in NQO1 , GST-M1 , GST-T1 and CYP3A4 in 469 Japanese patients with therapy-related leukemia/myelodysplastic syndrome and de novo acute myeloid leukemia Clin Cancer Res 2000 6 : 40914095 Ohno R, Kobayashi T, Tanimoto M, Hiraoka A, Imai K, Asou N, Tomonaga M, Tsubaki K, Takahashi I, Kodera Y, Yoshida M, Murakami H, Naoe T, Shimayama M, Tsukada T, Takeo T, Teshima H, Onozawa Y, Fujimoto K, Kuriyama K, Horiuchi A, Kimura I, Minami S, Miura Y, Kageyama H, Tahara T, Masaoka T, Shirakawa S, Saito H

Firstly, since it oxidises so rapidly, it has to be fixed immediately to avoid any degradation to its oxidised form glutathione disulfide (GSSG)

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