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What to expect week 1 of semaglutide is subtle biological tuning, not rapid fat melting

Water retention: Slight puffiness in the hands or feet, most common during the escalation phase and typically self-limiting

Keywords: glp-1/gip receptor agonists, intestinal hypomotility, obesity pharmcotherapy, small bowel obstruction, tirzepatide Introduction In recent years, glucagon-like peptide-1 (GLP-1) receptor agonists have gained widespread popularity for the treatment of obesity and type 2 diabetes due to their potent effects on weight loss, glycemic control, and cardiovascular risk reduction [1]

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