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10 g of Fibersol (the amount in 4 tsp of Flatter Me Fiber) was clinically shown to increase GLP-1 2x 30 minutes after a meal and remain elevated for 4 hours compared to a placebo in a randomized controlled trial

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Disulfide cross-linking validates the physiological relevance of the closed conformation, while electron microscopy (EM) and molecular dynamic (MD) simulations suggest a large degree of conformational dynamics of ECD that is necessary for binding GLP-1