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Additionally, Neurobion can be excreted into breast milk, and while the risks of overdose in newborns are not yet clear, high doses of Vitamin B6 (over 600mg per day) may cause a reduction in or cessation of breast milk production

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While necessary for purification and stability, high concentrations of some counter-ions, particularly TFA, can have their own biological effects (e.g., cytotoxicity in sensitive assays)