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184,185,186,187 Interactions with other pathways GLP-1 not only promotes the release of insulin but also enhances the response of pancreatic -cells to insulin through the PI3K/Akt pathway, thereby improving insulin signal transduction and increasing the sensitivity of peripheral tissues to insulin

It has been investigated for its effects on tendon-to-bone healing, gastrointestinal mucosal integrity, vascular development, and modulation of nitric oxide and growth-factor pathways in animal models

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