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BOC Sciences (2024)

Moreover, some exercise-mediated changes in adipose tissue, such as those in the MAPK pathway, have been observed to be transient, losing significance days after the last exercise session, indicating a need for sustained intervention or consistent polyphenol support to maintain benefits (60, 125)

Exposure to p28 produced a variable response in Np63 in Mel-29 and Mel-23 cells, first increasing then decreasing Np63 in Mel-29 cells and decreasing it at 72 hours in Mel-23, clearly suggesting the response was cell line dependent (Figure 8A)