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The pivotal clinical trials (SURPASS program for diabetes and SURMOUNT program for weight management) did not identify dental caries as a significant safety signal during systematic adverse event monitoring

If you are planning to conceive, semaglutide (Ozempic, Wegovy) should be stopped at least 2 months beforehand, whilst other GLP-1 medications require product-specific discontinuation guidancediscuss timing with your healthcare provider

doi:10.1001/jamadermatol.2025.2723 Image Credit: OpenAI

These working by gradually changing the color of just the outer layer of skin and do not really enter the bloodstream. Just be sure to remember that most of these do not contain SPF