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Mood-driven eating : Fluctuating hormones can trigger emotional eating and sugar cravings

Thus, the -MSH/MC1R/cAMP/MITF molecular signalling pathway is fundamental to melanin biosynthesis and to a great extent determines the type and amount of the melanin produced [4, 6]

In particular, TNF- is known to cause insulin resistance and the levels of TNF- are elevated in individuals with metabolic dysfunction-associated fatty liver disease (MAFLD), also referred to as metabolic dysfunction-associated steatotic liver disease (MASLD)

In humans it is synthesized in the liver, kidney, and brain and actively transported to other areas of the body