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Patients receive close medical supervision, goal-specific planning, and continuous motivation throughout their journey

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Lastly, although none of the PIONEER trials were specifically designed to assess semaglutide tablets in patients who were intolerant to metformin or in whom metformin is contraindicated, Health Canada semaglutide tablets considered PIONEER 1 to be of sufficient evidence and noted that this is aligned with the indication granted by other regulatory agencies

All participants received diet and exercise recommendations regardless of which treatment they were given