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Some research suggests that GLP-1 agonists may have anti-inflammatory effects that could theoretically influence the autoimmune process itself, though this remains speculative and has not been demonstrated in clinical trials specifically for thyroid autoimmunity

Combination therapy approaches If tirzepatide alone is insufficient, combination therapy may be the next step

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Protein intakes of 1.2 to 1.6 grams per kilogram body weight help preserve lean mass during weight loss while supporting satiety beyond what tirzepatide provides alone