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For the master trial focusing on obesity or overweight, 2,339 eligible adults who had at least one weight-related comorbidity but without diabetes were randomised in a 1:1:1:1 ratio to receive retatrutide in doses of 4 mg, 9 mg, 12 mg, or a placebo

Exercise at zone 2 intensity (where you can hold a conversation) for at least 100 minutes per week, plus add 1-2 weekly sessions of yoga or pilates

Appl Microbiol Biotechnol 101(5):21312141 Wilson AC, Thompson HJ, Schedin PJ, Gibson NW, Ganther HE (1992) Effect of methylated forms of selenium on cell viability and the induction of DNA strand breakage

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