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Kroner et al (49) demonstrated that elevated iron levels in microglia promote phagocytosis and drive a harmful M1 phenotype, which triggers the release of pro-inflammatory factors such as TNF-, IL-1, IL-6 and nitric oxide (NO), causing neuronal damage

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This divergence is clinically meaningful for research design: tirzepatide is the stronger tool for weight and glycaemic endpoint studies

L-Carnitine works by facilitating the movement of fatty acids into the mitochondria of cells, where they are oxidized to generate energy