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This has been suggested to underpin the effects seen after RYGB surgery on glycemia and appetite, although the reduction in fecal SCFAs as observed postoperatively in many studies [2,3,4,5] seems to contradict such a mode of action

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Furthermore, it has been revealed during several pre-clinical and clinical trials that RA-FLS plays a significant role in RA through the manufacturing of receptor activator of NF-B ligand (RANKL), which results in bone erosion through enhanced stimulation of osteoclast formation (Alam et al