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A further improvement was seen during the extension in those receiving NAC, although this failed to reach statistical significance compared with placebo, possibly due to the small numbers or due to the initial improvement being a placebo effect

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Is it safe to take carnitine while on thyroid medication

The phase 1b, 16-week, multiple-dose ascending trial (NCT05613387) showed a mean body weight reduction of 4.8%, 8.6% and 8.3% at OW doses of up to 2.4 mg, 4.8 mg and 9.0 mg, respectively [116]