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The synergistic potential of combining anti-inflammatory, barrier-repairing, and tissue-regenerating peptides mirrors the multi-mechanism nature of eczema itself

on 30 patients postulated that capability of exogenous GSH to cross cell membrane is very low

168 As reviewed by Brierley & Kelber, compounds like gingerol, menthol, and eugenol target TRP channels (e.g., TRPA1, TRPM8), which are responsible for pain and motility regulation in the GI tract

Similarly, it has been confirmed in PC-12 cells that berberine exerts a neuroprotective effect by activating the PI3K/AKT signaling pathway and Nrf2/HO-1 antioxidant signaling pathway (Zhang et al., 2017)