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In fact, it is one of the few antidepressants associated with weight neutrality or modest weight loss in some patients, making it a meaningful consideration for those concerned about the changes often seen with other antidepressants

GSDMD deficiency inhibits the expression and secretion level of CCL11 in vivo and in vitro In vitro observations verified that endothelial function and tube formation were exacerbated by the culture supernatants of GSDMD-KD macrophages