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For HIV-associated lipodystrophy, a 2009 study found that 120 g/kg biweekly treatment showed an improvement in visceral adipose tissue by 1015% over 24 weeks, but further development was not pursued [wong (2008) abstract]

Through this receptor it also shares insulin-like metabolic activity , including increased glucose uptake, which is the basis for its hypoglycemia risk

Not all patients qualify