glp-1 side effects eyes A potentially blinding condition is a very rare effect of the receptor agonist semaglutide (Ozempic, Wegovy, Rybelsus), the European Medicines Agency (EMA) concluded. https://www.medpagetoday.com/ophthalmology/generalophthalmology/115938?trw=no Blurry Vision from GLP-1 Medications:

Balance, our signature fiber matrix, helps slow carbohydrate absorption and supports healthy blood sugar levels already within the normal range as part of a balanced diet

This 2025 study supports the hypothesis that A

There are a variety of unimolecular dual GLP-1/glucagon receptor (GLP-1/GCGR) agonists in clinical development, based on the native peptides (glucagon,GLP-1, oxyntomodulin, exendin), including cotadutide (MEDI0382) [23, 24], SAR425899 [25], pegamodutide (OPK88003), and efinopegdutide (HM12525A)

This finding has direct implications for research protocol design: most published and structured study designs incorporate a rest period following the active phase to allow receptor sensitivity to normalize before any subsequent research cycle, rather than using continuous, uninterrupted administration