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Steroids have a risk of side-effects, including founder in certain populations of horses, as well as damage to the cartilage through ongoing use

If you have established cardiovascular disease or high risk, the SELECT trial data suggests staying on semaglutide provides ongoing protection

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These critical issues require urgent medical evaluation and management: Peptic ulcers - These are sores located in the stomach or small intestine Gastritis/esophagitis- This is an inflammation of the stomach or esophagus that causes erosion and bleeding Esophageal varices- These are enlarged, fragile veins in the esophagus, that are prone to rupture Mallory-Weiss Tear- A tear in the esophagus or stomach lining caused by forceful vomiting Gastrointestinal cancers- Cancers of the esophagus or stomach can also cause bleeding Symptoms of melena True melena (tarry, sticky, foul-smelling black stool) strongly indicates an upper GI bleed, requiring urgent medical evaluation