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To our knowledge, there was only one report to determine the efficacy of ALC for HE.28 However, we found that it revealed some insufficiency in methodology and unreasonable data for analysis

( B ) Analysis of plasma parameters (sodium, chloride, urea, creatinine, total cholesterol, glucose, triglycerides, glycerol levels) in saline controls (Saline, n = 9), saline-treated HI animals (HINT, n = 7), HI treated with Exendin-4 (Ex-4, n = 6) and HI treated with Semaglutide (Sema, n = 7), which showed no significant difference between groups except for a statistically significant increase in creatinine in all HI groups

Both treatments confirmed cardiovascular safety in this high-risk population, with tirzepatide providing similar protection to an established GLP-1 receptor agonist with proven cardiovascular benefit

Both followed a skincare routine combining an astaxanthin-based gel and sun protection in the morning and a 0.1% retinol serum in the evening, for six weeks