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Protective role of Metformin in preeclampsia via the regulation of NF-B/sFlt-1 and Nrf2/HO-1 signaling pathways by activating AMPK

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At the same time, aromatic amino acids (such as Trp, Leu, Phe, Tyr, Val, Ile) can stabilize active oxygen through direct electron transfer, and Tyr, Phe and Val can significantly enhance TIP's anti-tyrosinase activity (Nie et al., 2017

Cominetti C, de Bortoli MC, Garrido AB Jr, Cozzolino SM