One essential notion he advanced is the distinction between two phases in the development of tools (technologies, institutions): a first, in which they are primarily means for the empowerment and liberation of individuals, and a second, in which they become primarily self-referential ends, ultimately oppressive and enslaving of individuals (as illustrated in, e.g., transport by the shift from bicycles and motorized public transport to mass automobility)
not primarily appetite-driven (OUP Academic) Expected weight loss (this is where many people get misled) In major obesity trials: Semaglutide 2.4 mg weekly: ~14.9% mean weight loss at 68 weeks (STEP-1) (PubMed) Tirzepatide: ~15.0% to ~20.9% mean weight loss at 72 weeks , dose-dependent (SURMOUNT-1) (PubMed) AOD-9604s best-known human signal is kilograms, not double-digit percentages , and later studies did not sustain a strong obesity-drug profile
He adds, I pity the previous version of me that was on this roller coaster searching for his next hit all the time. Since beginning his longevity journey about two years ago, he touts he is at near perfect whole body health markers, based on measures of his biofluids, among other things
Dihexa (10mg) / Tesofensine (250mcg) / BPC-157 (125mcg) Tri-Compound Oral Research Formulation x 60 Tablets Oral solid-form research compound formulated for controlled analytical and investigational applications
