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doi:10.1073/pnas.0813409106, PMID: 19223582 Vali S, Mythri RB, Jagatha B, Padiadpu J, Ramanujan KS, Andersen JK, Gorin F, Bharath MM (2007) Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinsons disease: a dynamic model

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Activity Modification & Education Cross-training with low-impact activities (cycling, swimming, elliptical) during recovery Gradual return to higher-level sports as pain and function improve Comprehensive patient education on ergonomics, technique, and recurrence prevention 4

This also results in the opening of the mPTP leading to uncontrolled ROS production and disrupted synaptic maturation causing autistic behaviors [127]