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363,364 Similarly, GRP78 upregulation is detected in ALS spinal motor neurons, and region-specific UPR markers such as GRP58 and CHOP are found in prion diseases and HD, respectively

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Furthermore, melatonin combined with a ketogenic diet overcomes drug resistance to cisplatin and vincristine in BC-bearing mice by inducing apoptosis, inhibiting angiogenesis, lowering blood glucose, increasing ketone bodies, and downregulating resistance genes, achieving cure rates up to 70% 168

Then she learned about Functional Health Medicine, and everything changed