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Additionally, castration considerably decreased the expression of important antioxidant enzymes (AOEs) (GPx1, thioredoxin, SOD2, and peroxiredoxin 5) and markedly increased the expression of ROS-generating NAD(P)H oxidases

GLP-1 receptor agonists, such as Semaglutide (Ozempic, Wegovy)have proven effective in treating type 2 diabetes and obesity by mimicking GLP-1, a hormone that regulates glucose metabolism and appetite

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