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Raya-SandinoALuissintACKustersDHMNarayananVFlemmingSGarcia-HernandezVet alRegulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2

Tolvaptan, which is a V2-receptor antagonist, has been demonstrated in experimental studies and a large randomized controlled trial involving 1,445 patients with autosomal dominant PKD to limit the progression of the disease

In addition, there is evidence that pioglitazone reduces the risk of MI and acute coronary syndrome in patients with cardiovascular diseases (CVD) and patients with type 2 diabetes who had previous myocardial infarction [220,221,222]

Venn diagram analysis (Fig