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10.3389/fncel.2023.1213640 203 WangQ

"MOTS-c levels in human blood decline with age and correlate with insulin sensitivity, positioning the peptide not just as a metabolic tool but as a potential biomarker of mitochondrial vitality." On the exercise side, a pivotal finding came from studies measuring endogenous MOTS-c in human subjects

10.1002/adma.201900730 22 HallS.RudrawarS.ZunkM.BernaitisN.AroraD.McDermottC.et al (2016)

Anim Nutr 4(1):1116 Zhang CE, Wei W, Liu YH, Peng JH, Tian Q, Liu GP, Zhang Y, Wang JZ (2009) Hyperhomocysteinemia increases -amyloid by enhancing expression of -secretase and phosphorylation of amyloid precursor protein in rat brain