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4 important Ozempic drug interactions to be aware of "When using Ozempic (semaglutide), a GLP-1 receptor agonist primarily prescribed for managing type 2 diabetes and weight loss, it's important to be mindful of potential interactions with medications and supplements," confirms Jennie Stanford, MD, Obesity Medicine Physician and medical contributor for Drugwatch

Unlike small-molecule drugs such as aspirin or ibuprofen, which can tolerate wide temperature swings without losing effectiveness, peptides are proteins with complex three-dimensional structures that depend on precise folding to function