Presently, immunomodulatory actions are believed to play a central role in the renoprotective effects of GLP-1 RAs [3, 26,27,28]
Interestingly, the same study found that, in rats, tirzepatide suppressed lipid intake without affecting sucrose (carbohydrate) consumption in a choice-based assay, implying that the effects of these medications may be macronutrient specific (Geisler et al., 2023)
Biol Psychiatry 65 : 191197
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