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In type 2 diabetes, postprandial GLP-1 secretion may be reduced , leading to an impaired insulin response

Its dual GLP-1 and GIP receptor activation produced a 20.9% average body weight reduction at 72 weeks in the SURMOUNT-1 trial, and more recent SURMOUNT-5 head-to-head data confirmed its superiority over Semaglutide

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