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Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells
Cancer 11 , 325337 (2011)
Although quinone metabolites typically carry the risk of hepatotoxicity, previous studies have found that glucuronidation competes with this bioactivation pathway, forming a detoxification mechanism, which may be an important reason for its clinical safety profile (7,139)
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