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1 mg daily 0.75 mg daily 0.5 mg daily for 4 to 6 weeks Fresh injuries less than 2 weeks old, post-surgical recovery Fresh injuries often respond more dramatically than chronic conditions

Zhao and Dixon, 2009)

This, and the fact that APR-246 and system x C inhibitors have been safely trialled in humans 36,37 , should facilitate rapid translation of our findings to improve treatment outcomes for patients with mut-p53 cancers