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Sources: Cleveland Clinic and NCBI Bookshelf Who Should Take GLP-1 for Weight Loss

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Indeed, knockout mice for Stat5a/b genes exhibit similar defects as those caused by GH deficiency, at least in terms of body and tissue growth 31,32,33

In several RCTs, GLP-1 receptor agonists were compared with insulin or insulin-based intensification strategies, therapies that have been associated with hyperinsulinemia and potential pro-proliferative signaling