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Selenium status has also been inversely correlated in PCOS with insulin resistance and lipid peroxidation, further supporting a role in metabolic protection

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Endometriosis often coexists with adenomyosis, and both conditions share immunological alterations, including abnormal immune cell function and pro-inflammatory cytokine secretion, which collectively disrupt reproductive processes ( 2.2.1 Immune cell alterations Macrophages are key drivers of immune dysfunction, constituting over 50% of immune cells in the peritoneal fluid of affected women