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This naturally occurring peptide, called exendin-4, shared structural similarities with human GLP-1 (glucagon-like peptide-1), a hormone our pancreas produces to regulate blood sugar and satiety

Semaglutide works on the GLP-1 pathway

NAPDH Oxidase converts oxygen to Super Oxide (O 2 ) mainly in neutrophils Myeloperoxidase (MPO) converts peroxide (H2O2) into Hydrochloric Acid (HOCl) mainly in neutrophils Fenton Reaction generates Hydroxide (OH-) from peroxide (H2O2) using iron Superoxide Dismutase (SOD) converts Super Oxide (O 2 ) to peroxide (H2O2) Glutathione convert Hydroxide (OH-) to water Catalase converts Peroxide (H2O2) to water We will see in the immunology section that that a defect in NADPH Oxidase causes Chronic Granulomatous disease