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In some embodiments, an otic composition or formulation disclosed herein comprises less than about 20 ppm of water

Epithalon protects aging oocytes from this damage

Rodents consuming prebiotics like bovine milk oligosaccharides, oligofructose-enriched inulin, spirulina platensis, and a combination of Fructooligosaccharide/Galactooligosaccharide have exhibited decreased plasma levels of lipopolysaccharides, lower serum concentrations of pro-inflammatory cytokines, diminished intestinal inflammation, and enhanced tight-junction integrity [93,94,95,96,97]

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