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It particularly highlights the pivotal roles of reactive oxygen species, impaired mitochondrial metabolism, epigenetic dysregulation, and alterations in the ovarian microenvironment

Lp-PLA2 diffre des autres membres de la phospholipase A2, car elle ne ncessite pas de calcium pour son activit enzymatique, et dans sa spcificit de substrat, car elle hydrolyse prfrentiellement la chane acyle sn-2 tronque par oxydation des phospholipides hydrosolubles

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In a rat model of MCAO, RIPostC reverses GPX4 reduction and ACSL4 overexpression by increasing ketone body production, thereby alleviating nerve damage