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The clinical data reflects this: a 2022 retrospective analysis of 340 patients receiving lipotropic injections as part of a medically-supervised weight loss program found that those who maintained a 500-calorie daily deficit lost an average of 8.4% body weight over 16 weeks, compared to 5.1% in matched controls on caloric restriction alone

In this nomenclature, the numbers denote the weight percentages (wt%) of polymer (HPMC-C12), nanoparticles (PEG-PLA), and Tween 20 (surfactant), respectively, while the remainder is buffer (phosphate buffered saline or PBS)