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When to Discuss a Dosage Change You may need to review your dosage with your provider if: You experience persistent swelling, numbness, or tingling IGF-1 or glucose levels move outside your target range Youre not seeing expected results after several months of consistent use Providers may adjust the timing, switch formulations, or combine tesamorelin with peptides such as CJC-1295 or Ipamorelin for synergistic effects

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