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Impaired recovery after chronic morphine in wild type locus coeruleus neurons was reversed and resembled that in the - arrestin2 knockout either by disrupting GRK2 function or by inhibition of dynamin function with intracellular inhibitors

Rigorous pharmacological characterization of herbal formulations through chemical profiling, target validation, and network pharmacology will be crucial for linking traditional theory with modern biomedical mechanisms

JC virus is an etiologic agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease