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doi: 10.18632/aging.101465

It was among the first reports of a small molecule reproducing the metabolic effects seen with earlier NNMT-blocking approaches

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Focus on: Lean protein at each meal to preserve muscle mass during weight loss Vegetables and fiber to support digestion and reduce constipation Adequate hydration , ideally 64 oz (2 liters) of water or more daily Small, frequent meals rather than large portions, especially during dose escalation Foods to limit or avoid during early treatment include greasy or fried foods, large servings of red meat, very sugary foods, and carbonated beverages, all of which commonly worsen nausea or reflux