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Because every stage plays a role in limiting side effects, patients generally see the best experience when they follow their providers schedule rather than trying to move faster on their own

Patients are also most likely to experience problems when they start on the drug or when they step up to a higher dosage

Food and Drug Administration (FDA) Consumer Updates on GLP-1 Receptor Agonist Efficacy, Approved Semaglutide High-Dose Guidance, and Public Safety Alerts (USA Gov)

In trials to assess semaglutides effectiveness for reducing the risk of major cardiovascular events in adults, increases in total bilirubin greater than or equal to 3 times the upper limit of normal were seen in .3% of people taking Wegovy versus .2% of people taking the placebo