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Most clinical trial data supports use of 3 to 6 months without long-term safety concerns

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This is why many people use it as a sleep aid

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To mitigate this drawback, the pharmacological administration of GIP, primarily known for its insulinotropic and mild appetite-suppressing properties [7], is also suggested to have an anti-emetic effect, potentially allowing GIP co-agonism to increase tolerability to the GLP-1 component [8]

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