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RCD inhibition seems to be a promising treatment strategy in the early stages of liver disease

Captopril, an angiotensin-converting enzyme inhibitor, is widely used in clinical practice to treat hypertension, MI, and congestive heart failure and is effective in attenuating left ventricular (LV) dilatation, ameliorating LV ejection fraction and improving cardiovascular morbidity and mortality [237, 238]

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Studies have shown that it can resist the toxicity of APAP to hepatocytes by activating Nrf2