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The activation of NRF-2 in liver suppresses the synthesis of fatty acids [70], as observed in this study that included experimental feeding with 8-week-old NRF-2 null mice, and wild-type mice fed experimentally, observing the mRNA of sterol regulatory element-binding protein 1-c and fatty acid synthase as highly expressed in NRF-2 null [71], concluding that the protective action is afforded by the increase of AR
then some types migrate to damage neighboring cells
Types of vesicles used such as MLV, SUV or large unilamellar vesicles (LUV) and their encapsulation efficiency varies greatly from 1% for SUVs to 88% for MLVs
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